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MUST BET: Bills Moneyline Sunday Night Football Picks Based Off Awesemo’s Expert NFL Betting Tool

Capping off a packed NFL Week 5 Sunday will be the Buffalo Bills taking on the Kansas City Chiefs. With the highest NFL betting total of the week, this is expected to be an extremely exciting game with plenty of offensive fireworks. The following Bills – Chiefs preview will provide the current odds, betting trends, and best NFL bets for the Week 5 Sunday Night Football matchup.

NFL Best Bets & Odds: Week 5 Sunday Night Football

Buffalo Bills vs. Kansas City Chiefs
Date: Sunday, Oct. 10, 2021
Time: 8:20 p.m. EST
Venue: GEHA Field at Arrowhead Stadium — Kansas City, Mo.
Coverage: NBC

After losing to the Steelers in Week 1, the Bills have been the most dominant team in the NFL, outscoring their opponents 118-21 over the past three weeks. The competition has not been great, but their level of focus proves how good they are. Offensively they are more of a balanced attack, running the football and targeting more receiving options. Defensively they have had two shutouts over the past three weeks.


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The Chiefs are coming off a dominant win, but it came against the Eagles, and they have not shown title-contending play thus far. However, the offense has not been the problem, and their pass-catching group will get better this week, with the debut of Josh Gordon. The defense is the massive issue in Kansas City. They have surrendered a league-worst 6.9 yards per play and must find a way to get off the field so Patrick Mahomes can get on it.

Bills vs. Chiefs Betting NFL Picks + Odds Shopping

Using Awesemo’s OddsShopper tool, we can easily compare the NFL odds for Bills vs. Chiefs betting across the major sportsbooks. Make sure to check out the OddsShopper tool yourself to get the most up-to-date odds.

Bills vs. Chiefs NFL Betting Trends

  • Buffalo is 3-1 against the spread.
  • The over is 1-3 for the Bills.
  • Kansas City is 1-3 against the spread.
  • The over is 3-1 for the Chiefs.

Bills vs. Chiefs Betting Stats

  • Buffalo is averaging 33.5 points per game (T-No. 2 in the NFL).
  • Buffalo is surrendering 11.0 points per game (No. 1 in the NFL).
  • Kansas City is averaging 33.5 points per game (T-No. 2 in the NFL).
  • Kansas City is surrendering 31.2 points per game (No. 31 in the NFL).

Bills vs. Chiefs NFL Best Bet

We are using the new Awesemo NFL Betting Model to figure out what the best bet for Sunday Night Football is tonight. According to the model, betting the Bills moneyline is the clear best bet to place, giving it a 11.6% ROI. The Chiefs are currently favored by 3 at home and are expected to win the game. However, this game feels like a coin flip. If the Kansas City defense continues to struggle, there could be an upset. While betting the spread would protect Bills bettors from a game-winning field goal, the moneyline is the most profitable bet according to the tool.

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