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Colorado-Oregon Pick & Prediction: Buy Saturday’s Total (Sept. 23)

The No. 19 Colorado Buffaloes will visit the No. 10 Oregon Ducks on Saturday in one of the best games on the Week 4 card. Every week, we’ll post our top college football picks starting on Monday and provide an update before each game — you can check out all of our college football Week 4 picks here. Let’s dig into today’s Colorado-Oregon odds as we make our predictions and pick the best college football Week 4 bet!

Looking for more 2023 college football predictions? OddsShopper’s experts are here to break down this college football season — make sure to check out the rest of our college football articles, including our best bets for Week 4. If you still need more picks, our market-based betting model might just be for you — you can even try it out now!

Colorado-Oregon Pick & Betting Prediction | College Football Week 4

Colorado-Oregon Betting Odds

Odds via FanDuel Sportsbook
Colorado: +720 | Oregon: -1200
Colorado +21.5: -120 | Oregon -21.5: -102
Over 70.5: -105 | Under 70.5: -115
Expert: Ben Rasa

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Colorado-Oregon Pick & Prediction

The No. 19 Colorado Buffaloes are a big-time story every week regardless of their opponents, but seeing the No. 10 Oregon Ducks on the schedule is sure to amp up the excitement. This is by far the toughest test Deion Sanders’ squad has faced and having to play it on the road makes it that much tougher. After a huge upset in Week 1 against TCU, the Buffs crushed Nebraska and then hung on against in-state rival Colorado State in a dramatic double-overtime finish. Getting taken to the wire against an inferior CSU team isn’t encouraging, but their record remains undefeated heading into Oregon. Looking at the line, we see that is expected to change, with Oregon sitting at around a 21-point favorite in this spot.

If Colorado is going to pull an upset, then Shedeur Sanders needs to continue his Heisman-caliber play at quarterback. So far this season Sanders has 10 touchdowns to just one interception and is cruising past 300 yards in each game. The offense has put up 36 or more points in all three games, and they’ll probably need to do that again here. One of the biggest problems is that their two-way superstar, Travis Hunter, suffered an injury and won’t be available. That’s a major loss for a team whose depth could be brought into question here.

On the other side, we have a 3-0 Oregon team back at home where they are almost unbeatable. They survived a dramatic 38-30 win at Texas Tech and then destroyed two cupcakes. They even hung 81 on poor FCS Portland State. Quarterback Bo Nix might not get the most spotlight on a national stage, but he is an elite signal caller who leads this offense. He has a ton of weapons on the outside. Oregon’s defense will be tested here and after losing a few key players to graduation, and it remains to be seen how much they can slow Colorado’s offense.

Now that we’ve talked about the teams let’s get into the potential betting avenues. Looking at OddsShopper’s tools, we were able to find Oregon as a 20.5-point favorite in the early week column, but we are unable to find them there now. The best price is Oregon -21.5 at -102 via FanDuel Sportsbook. However, the over is a reasonable position with where the market is at now. The current number sits at 70.5, and although that is high, I just do not see any way Colorado can slow down this Oregon offense. If Colorado is able to manufacture a handful of touchdowns, the over should be no problem to clear with the points put up on both sides. I’ll call for Oregon to score early and often here en route to a comfortable home win with the scoreboard lighting up.

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Colorado-Oregon Week 4 Pick: Over 70.5 -105 at FanDuel

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Ben Rasa

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