Skip to content
logo
Search Icon
​
Log InSign Up
Top Bets
Top Bets
My Bets
My Bets
Portfolio Lab
Portfolio Lab
Help
Help
Categories MLB

MLB Home Run Picks: How to Attack Monday’s Slate (Sept. 18)

Updated September 18, 2023 | 3:07 pm CDT by Isaiah Sirois
The best MLB home run picks and bets today include one player for the Padres, who will take on the Giants in San Fran...

As teams like the Baltimore Orioles and Tampa Bay Rays secure playoff spots, the MLB rolls on with another exciting slate of meaningful baseball. I want action on one member of the Reds, and OddsShopper’s model wants action on one member of the Orioles. Let’s dive right into today’s best MLB home run picks and bets for Twins-Reds and Orioles-Astros. We’re trusting Christian Encarnacion-Strand at home tonight.

Few sweats are more fun than home run bets. If you want to start making money on your home run picks, OddsShopper has you covered. We post daily home run articles and have a strategy guide. What’s more, our MLB bet shopping pages integrate data from our industry-leading betting model to identify home run picks with positive expected value (+EV) each day. If you’re hungry for more than just the picks we post for free, sign up for OddsShopper Premium today — new users can get their first month for 70% off.

caesars sportsbook promo code

Best MLB Home Run Bets & Picks Today for Monday, September 18

Twins-Reds Home Run Pick

When: 6:40 p.m. ET
Where: Great American Ball Park, Cincinnati

Isaiah’s Target: Christian Encarnacion-Strand at DraftKings

A couple of batters stand out from tonight’s Twins-Reds game, which will be played in the hitter-friendly Great American Ball Park with 6.9 mph winds blowing out through right-center field. The Twins will start RHP Joe Ryan, who has coughed up a team-worst 28 actual and 29.3 expected home runs, a whopping 36 of which would’ve cleared the fences at Great American. The Reds will start recent call-up RHP Connor Phillips, who has coughed up three actual and 1.9 expected home runs in just 8.2 innings pitched, three of which would’ve gone yard at Great American.

The batter I’m ultimately backing in this matchup is RHH Christian Encarnacion-Strand for the Reds. Encarnacion-Strand, another recent Cincinnati call-up, owns a .474 xSLG with eight actual and 6.9 expected home runs to his name. He has now homered in back-to-back contests heading into tonight’s opening matchup with the Twins. All eight of Encarnacion-Strand’s home runs have come with him lined up against RHPs like Ryan. He is slashing a monstrous .284/.338/.500 against them this year through 134 at-bats. Over the last 15 days, Encarnacion-Strand has slashed .365/.400/.667.

Ryan has been a pumpkin at points this year, and his 36 expected home runs at Great American make him a fantastic target on the betting markets tonight. The 27-year-old pitcher has yet to take the mound at this park and may struggle in his first trip here. His 3.44 xERA is solid, but the fastball-dependent pitcher isn’t well-suited for a park like this one. It’s all the more concerning that his ERA jumps to 4.67 on the road, where he has coughed up 16 home runs, and that RHHs are slashing .258/.284/.503 against him with 20 home runs.

New to DraftKings? Take advantage of our DraftKings promo code: new users can get $200 in bonus bets after placing a $5 wager! 

Best MLB Home Run Bet: Christian Encarnacion-Strand +450 at DraftKings

Bet $5 on the Chicago White Sox and Get $150 in Bonus Bets instantly at DraftKings!

21+ Gambling Problem? Call or text 1-800-GAMBLER or Chat 24/7 at ncpgambling.org/chat

Astros-Orioles Home Run Pick

When: 8:10 p.m. ET
Where: Minute Maid Park, Houston

OddsShopper’s Target: Anthony Santander at FanDuel

Let’s turn now to OddsShopper’s pick, which comes in this evening’s Astros-Orioles game. The model wants a ticket on SH Anthony Santander at the price of +350 (22.2%), a line you’ll only find at FanDuel. The 28-year-old outfielder has hit a team-high 27 actual and 30.7 expected home runs this season. Note that 10 other home run picks are popping with positive expected value in OddsShopper’s market-based model; you can even get 70% off your first month!

Santander will take on veteran RHP Justin Verlander tonight. Although Verlander is a savvy pitcher — any three-time Cy Young winner is — he has struggled with the long ball of late. Verlander has coughed up 18 home runs this season, seven of which have been hit in his last five starts. Verlander has allowed 17.5 expected home runs on the year, but 20 of those hits would’ve cleared the fences in Houston, a less pitcher-friendly park than New York’s Citi Field.

The model doesn’t care about stats and splits — this is purely a market-based edge. DraftKings lists this home run bet at odds of +275 (26.7%). Our model thinks a fair price is +334 (23%), so we’re beating the market and getting some value by playing this MLB home run pick at +350 (22.2%) via FanDuel Sportsbook. This number may not remain on the market forever, so if you want to tail one of the model’s top home run picks today, get your action down soon!

Best MLB Home Run Bet: Anthony Santander +350 at FanDuel

Today’s Best MLB & Sportsbook Promotions

React App

Best Offers in Ohio

Ohio
State

Categories MLB
Expert NFL Prediction: Lindy’s Best Bet for Saints-Panthers Monday Night Football (September 18)
Week 2 Monday Night Football Promo Codes: Bet365, Caesars Sportsbook, Underdog Fantasy
Isaiah Sirois

Author

Isaiah Sirois

Isaiah Sirois is a sports betting analyst at OddsShopper specializing in basketball, football and motorsports. Basketball is Isaiah’s favorite sport to handicap, and he has covered NBA, WNBA, NCAA and FIBA markets for OddsShopper and other sites. However, Isaiah’s favorite sport to follow is auto racing, and you can usually find him watching NASCAR or IndyCar on Sundays. He will be a fan of Team Penske and Ford Performance until the end of time. Isaiah graduated with a bachelor’s degree in history from Emory University and briefly attended Vanderbilt Law School before dropping out to work at OddsShopper.

Next Story

Open Championship Odds, Picks & Betting Predictions (2025)

Trending & Related

Home Run Derby Betting Strategy: How Experts Bet the HR Derby

Best MLB Prop Bets Today: Strikeout Props & More From OddsShopper Experts (June 22)

Best MLB Prop Bets Today: Video Breakdown of Portfolio EV’s Top Strikeout Props (June 20)

Betting 101

PrizePicks Cheat Sheet Today: How to Use a PrizePicks Optimizer

Positive Expected Value Explained: How to Find Positive EV Edges in Sports Betting

Underdog Fantasy Cheat Sheet: How to Find the Best Picks Today

ProphetX Sportsbook: How This Peer-to-Peer Betting App Is Changing the Game

Sports Betting Resources

  • Positive EV NFL Bets
  • Expert NFL Picks
  • Live NBA Odds
  • Positive EV NBA Bets
  • Expert NBA Picks
  • Live NFL Odds
  • NFL Parlay Calculator
  • Positive EV MLB Bets
  • Expert MLB Picks
  • Positive EV College Football Bets
  • Expert College Football Picks

Featured Articles

Open Championship Odds, Picks & Betting Predictions (2025)
July 16, 2025 8:42 am | Ben Rasa
Get a 7-DAY FREE TRIAL Of Portfolio EV Today!
July 13, 2025 7:47 am | Sam Smith
What is Dinger Tuesday? How to Beat FanDuel’s Promotion
July 10, 2025 11:30 am | Isaiah Sirois
MLB Betting Strategy: 5 Tips for Winning on MLB Betting Sites
July 7, 2025 8:29 am | Dave Loughran
What is a Futures Bet? How to Make Money Betting on Futures
June 20, 2025 9:41 am | Isaiah Sirois
US Open Odds, Picks & Betting Predictions (2025)
June 11, 2025 9:44 am | Ben Rasa

Related Articles

Home Run Derby Betting Strategy: How Experts Bet the HR Derby
July 14, 2025 10:04 am | Sam Smith
Best NRFI Bets Today: Winning Strategy for First Inning Betting
July 13, 2025 8:08 am | Sam Smith
MLB Home Run Betting Strategy: How to Profit on Home Run Bets
July 13, 2025 7:53 am | Isaiah Sirois
Underdog Fantasy Pick’em Predictions Today: Brandon Woodruff (July 12)
July 12, 2025 9:40 am | Danny Burke
Underdog Fantasy Pick’em Predictions Today: Dansby Swanson (July 9)
July 9, 2025 1:06 pm | Danny Burke
MLB Betting Strategy: 5 Tips for Winning on MLB Betting Sites
July 7, 2025 8:29 am | Dave Loughran

PrizePicks Cheat Sheet Today: How to Use a PrizePicks Optimizer
July 16, 2025 9:55 am
How to Bet on Golf Outrights: Tips, Strategy & Expert Advice
July 16, 2025 8:42 am
Open Championship Odds, Picks & Betting Predictions (2025)
July 16, 2025 8:42 am
Positive Expected Value Explained: How to Find Positive EV Edges in Sports Betting
July 16, 2025 8:41 am
Chalkboard Fantasy Legal States
July 15, 2025 2:20 pm
Underdog Fantasy Cheat Sheet: How to Find the Best Picks Today
July 15, 2025 1:16 pm
Home Run Derby Betting Strategy: How Experts Bet the HR Derby
July 14, 2025 10:04 am
ProphetX Sportsbook: How This Peer-to-Peer Betting App Is Changing the Game
July 13, 2025 12:25 pm
What is Portfolio EV? Guide to +EV Sports Betting
July 13, 2025 8:09 am
Best NRFI Bets Today: Winning Strategy for First Inning Betting
July 13, 2025 8:08 am

How Can I Find the Best Sports Betting and DFS App Bonuses?

If you're a new sports bettor, it's hard to know where to start. In fact, it's simpler than it seems, because there are incredible sportsbook bonus codes and DFS app promo codes that are expressly designed to help new players get started building a bankroll. As a new player, it's often correct to focus on taking advantage of as many of these offers as you can. Even better, having access to more books lets you take advantage of line shopping so that you can always get the best payout for your winning bets. Books like BetMGM and bet365 have great first-bet offers for new players. On the DFS App side, operators like Underdog and Sleeper offer matches on your first deposit up to a certain amount. Use the links below to explore the best sportsbook promo codes. Once you get signed up with a bonus, make sure to use OddsShopper's Free Bet Converter to maximize your beginning bankroll

Best BetMGM Bonus Code

Get a bonus code for BetMGM

Best Caesars Sportsbook Promo Code

Get a promo code Caesars Sportsbook
DraftKings Promo Code

Best DraftKings Promo Code

Get a promo code for DraftKings

Best FanDuel Promo Code

Use a promo code for FanDuel

Best PrizePicks Promo Code

Claim a promo code for PrizePicks

Best UnderDog Fantasy Promo Code

Get a promo code for UnderDog

Join the ranks of the OddsShopper Hall of Fame

  • Free Expert Picks

    • Free NBA Picks
    • Free MLB Picks
    • Free NFL Picks
    • Free NHL Picks
    • Free NCAAB Picks
    • Free NCAAF Picks
    • Free Golf Picks
    • Free UFC Picks
    • Free EPL Picks
    • Free Tennis Picks
    • Free WNBA Picks
  • Positive EV Bets

    • Positive EV NBA Bets
    • Positive EV MLB Bets
    • Positive EV NFL Bets
    • Positive EV NHL Bets
    • Positive EV NCAAB Bets
    • Positive EV NCAAF Bets
    • Positive EV Golf Bets
    • Positive EV UFC Bets
    • Positive EV EPL Bets
    • Positive EV Tennis Bets
    • Positive EV WNBA Bets
  • Betting Tools

    • Arbitrage Opportunities
    • Parlay Builder
    • PrizePicks Entry Builder
    • Underdog Entry Builder
    • Sleeper Entry Builder
    • Free Bet Converter
  • Articles

    • All Articles
    • NBA Articles
    • NFL Articles
    • NCAAF Articles
    • MLB Articles
    • PGA Articles
    • NHL Articles
    • NASCAR Articles
    • MMA Articles
  • Betting Calculators

    • Expected Value Calculator
    • Hold Calculator
    • Parlay Calculator
    • Odds Converter
  • Live Odds

    • Live NBA Odds
    • Live MLB Odds
    • Live NFL Odds
    • Live NHL Odds
    • Live NCAAB Odds
    • Live NCAAF Odds
    • Live Golf Odds
    • Live UFC Odds
    • Live EPL Odds
    • Live Tennis Odds
  • Sportsbook Promo Codes

    • BetMGM Bonus Codes
    • Bet365 Bonus Codes
    • FanDuel Promo Codes
    • DraftKings Promo Codes
    • Caesars Promo Codes
    • BetRivers Promo Codes
    • Sleeper Fantasy Promo Codes
    • Underdog Fantasy Promo Codes
    • Betr Picks Promo Codes
  • About Us

    • Contact Us
    • Terms of Use
    • Privacy Policy
    • Stokastic
OddsShopper Logo
© 2024 Stokastic.All Rights reserved.
This site contains commercial content, We may be compensated for the links provided on this page. The content on this page is for informational purposes only. OddsShopper makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event.Please play responsibly. Only customers 21 and over are permitted to play. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.