OddsShopper’s Expert NFL AI walks you through the best betting odds, trends, and predictions for the Detroit Lions’s matchup versus the Buffalo Bills.
The Buffalo Bills will be the visiting team versus the Detroit Lions, with kickoff at 11/24/2022 12:30 PM ET.
Buffalo Bills vs. Detroit Lions Betting Odds
| Team | Moneyline | Spread | O/U |
|---|---|---|---|
| Detroit Lions | +360 | +9.5, -104 | Over 54.5, -110 |
| Buffalo Bills | -460 | -9.5, -118 | Under 54.5, -110 |
The Buffalo Bills are favored in this matchup with -460 odds for the moneyline and -118 odds for the -9.5 spread on FanDuel.
The Detroit Lions are +9.5 point underdogs, with -104 odds and +360 odds for the moneyline in this matchup vs the Buffalo Bills.
Moneyline Odds
| Bet Side | BetMGM | Caesars | DraftKings | FanDuel | PointsBet | Unibet |
|---|---|---|---|---|---|---|
| Detroit Lions | +350 | +335 | +340 | +360 | +330 | +350 |
| Buffalo Bills | -450 | -440 | -425 | -460 | -425 | -420 |
Moneyline trends
- The Detroit Lions have not covered the Moneyline in 2 of their last 2 Home games (ROI: -100.0%)
- In the last 2 of 2 games, the Detroit Lions have not covered the Moneyline bet (ROI: -100.0%)
- In the last 2 of 3 Away games, the Buffalo Bills have hit the Moneyline bet (ROI: 10.7%)
- In the last 2 of 3 games, the Buffalo Bills have covered the Moneyline bet (ROI: 10.7%)
Point Spread Odds
| Bet Side | BetMGM | Caesars | DraftKings | FanDuel | PointsBet | Unibet |
|---|---|---|---|---|---|---|
| Detroit Lions | +9.5, -110 | +9.5, -110 | +9.5, -110 | +9.5, -104 | +9.5, -105 | +9.5, -109 |
| Buffalo Bills | -9.5, -110 | -9.5, -110 | -9.5, -110 | -9.5, -118 | -9.5, -110 | -9.5, -112 |
Point Spread trends
- The Buffalo Bills have not covered the Point Spread in 2 of their last 3 Away games (ROI: -36.1%)
- The Buffalo Bills have not covered the Point Spread in 2 of their last 3 games (ROI: -36.1%)
Total Odds
| Bet Side | BetMGM | Caesars | DraftKings | FanDuel | PointsBet | Unibet |
|---|---|---|---|---|---|---|
| Over | 54.5, -110 | 54.5, -110 | 54.0, -110 | 54.5, -110 | 54.5, -107 | 54.5, -110 |
| Under | 54.5, -110 | 54.5, -110 | 54.0, -110 | 54.5, -110 | 54.5, -107 | 54.5, -110 |
Our OddsShopper AI Model Pick Recommendation:
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Our Favorite Player Props for the Buffalo Bills vs. Detroit Lions Matchup
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Player Prop Trends
- In the last 2 of 3 games, Nyheim Hines has covered the Total Receiving Yards Under bet (ROI: 26.2%)
- In the last 2 of 2 games, Nyheim Hines has covered the Total Receptions Under bet (ROI: 89.3%)
- Nyheim Hines has hit the Total Rushing + Receiving Yards Under in 2 of his last 3 games (ROI: 23.6%)
- In the last 2 of 2 games, Nyheim Hines has covered the Total Rushing Yards Under bet (ROI: 88.1%)
- Devin Singletary has not hit the Total Receiving Yards Under in 1 of his last 2 games (ROI: -9.7%)
Looking for an edge on this NFL matchup featuring the Buffalo Bills vs Detroit Lions?
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