If you’re betting on MLB today, one of the fastest-growing and most exciting markets is the first inning. Below are the two best NRFI bets today, including one NRFI and one YRFI, based on expected value, pitching matchups and offensive trends. These first-inning plays offer real statistical edge and should be at the top of your betting card for April 22.
NRFI Bets Today: Best No Runs First Inning Picks
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Dodgers vs. Cubs | NRFI Bets Today
Dustin May takes the mound for Los Angeles with a sparkling 1.06 ERA and a WHIP below 0.80. He’s been nearly untouchable early in games, keeping hitters off base and avoiding big mistakes. On the other side, Chicago sends out Shota Imanaga, who has quietly become one of the most effective starters in the National League. With a 2.22 ERA and a WHIP just under 1.00, he has stifled opposing hitters, especially early in outings.
The Dodgers offense, despite being loaded with MVPs, has struggled in the first inning relative to its usual standards. Meanwhile, the Cubs lineup has been hot, but May is the type of pitcher who can neutralize that momentum quickly.
At -110, the NRFI for Dodgers-Cubs offers great value. The implied probability is around 53%, but the dominance of both starting pitchers suggests the true likelihood of a scoreless first inning is even higher. That makes this one of the best NRFI bets today.
Best NRFI/YRFI Bet: No Runs First Inning (-110, DraftKings)
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Rangers vs. Athletics | YRFI Bets Today
The game total is set at 10.5 runs, the highest on the board today — a clear sign that oddsmakers expect fireworks. On the mound, Patrick Corbin starts for Texas. Despite a few bounce-back starts, Corbin still carries a WHIP near 1.40 and is historically vulnerable in the first inning. The Athletics counter with Osvaldo Bido, who has outperformed expectations with a 2.61 ERA but has a much higher expected ERA (4.46), indicating regression is coming.
The Rangers bring a dangerous top of the order featuring Marcus Semien and Corey Seager, both capable of doing damage instantly. The Athletics, while young, have actually been above average in early-inning production this year and aren’t shy about jumping on pitchers early.
Add in favorable weather conditions (wind blowing out in Sacramento), and you have the perfect setup for a first-inning run.
Best NRFI/YRFI Bet: Yes Runs First Inning (-145, Fanatics)
