The NFL Week 10 Sunday slate ends with the Los Angeles Chargers at the San Francisco 49ers. The Christian McCaffrey and Jimmy Garoppolo prop lines offer significant value in this Sunday Night Football game. Let’s analyze the best prop bets for McCaffrey and Garoppolo in the Chargers-49ers matchup.
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Best Chargers-49ers Prop Bets
The 49ers made a statement when they acquired running back Christian McCaffrey from the Carolina Panthers at the trade deadline. San Francisco traded RB Jeff Wilson Jr. to the Miami Dolphins knowing that Elijah Mitchell would eventually return from IR. This will be the first game that McCaffrey and Mitchell will play together for the 49ers and they’re ready to shred one of the worst run defenses in the NFL.
The Chargers have allowed several long runs through eight games. Last week, Atlanta Falcons running back Tyler Allgeier broke off a 44-yard run on the third play of the game. They’ve allowed an opposing running back to break off a run of at least 17 yards every game except one. Seattle Seahawks rookie Kenneth Walker III showed off his explosive speed with a 74-yard touchdown run in Week 7.
With the Panthers, McCaffrey surpassed this line in five of eight games this season, plus two weeks ago with the 49ers. Mitchell is expected to chip into McCaffrey’s workload but they’ll be part of the most run-heavy team of the last few seasons under coach Kyle Shanahan.
Best Chargers-49ers Prop Bet: Christian McCaffrey Over 17.5 Longest Rush -105 (DraftKings)
Jimmy Garoppolo and the 49ers offense are back at full strength and will look to make a statement to the rest of the NFC on Sunday Night Football. The 49ers are off a bye week and will continue to work McCaffrey into the offense. A run-heavy game plan is on Shanahan’s mind as the Chargers allow the fourth most rushing yards per game.
Garoppolo is the prototypical game manager. He doesn’t put up flashy numbers but wins games. He is 49-21 in 70 regular-season games with four wins in the playoffs. This season, he’s averaging 240 passing yards and has led the 49ers to 12th in time of possession on offense. Wide receiver Deebo Samuel returns after missing one game due to a hamstring injury sustained in Week 7. Samuel will be another option to line up in the backfield and has the ability to take one for a touchdown at any time.
The Chargers have held the last three opposing quarterbacks under their passing-yard line, for an average of 206 yards, third best during that span. The 49ers come into this game with fresh legs and as 7.5-point favorites in front of their home crowd. Garoppolo is under this line in four of seven games, including his last game against the Los Angeles Rams, when Christian McCaffrey ran the ball 18 times.
Best Chargers-49ers Prop Bet: Jimmy Garoppolo Under 243.5 Yards Passing -115 (DraftKings)
