Cleveland Guardians vs Chicago White Sox Home Run Picks Today (6/22)
In Summary
- Colson Montgomery is the headline home run bet for Cleveland Guardians vs Chicago White Sox — best price +370 at Unibet.
- We compared every sportsbook's "to hit a home run" price for this game; the table below shows where each play pays the most.
- A home run prop's payout swings a lot book to book, so always take the best available number — that's the whole edge.
See the full slate: all of today's best home run bets, ranked by price, are in our MLB Home Run Picks Today hub.
Here are the top home run bets for Cleveland Guardians vs Chicago White Sox on June 22, 2026, with the best price on each across 100+ sportsbooks. "To hit a home run" is the over 0.5 home runs market; the odds below are the best available right now, so shop them on the OddsShopper home run odds screen before you bet.
Best Home Run Bets for This Game
| Player | Best HR Price | Best Book | Implied | Books |
|---|---|---|---|---|
| Colson Montgomery (CHW) | +370 | Unibet | 21.3% | 31 |
| Rhys Hoskins (CLE) | +412 | DraftKings | 19.5% | 31 |
| Miguel Vargas (CHW) | +422 | DraftKings | 19.2% | 31 |
| Kyle Manzardo (CLE) | +540 | Unibet | 15.6% | 31 |
| Andrew Benintendi (CHW) | +550 | Bet365 | 15.4% | 30 |
| David Fry (CLE) | +625 | Bet365 | 13.8% | 27 |
| Kyle Teel (CHW) | +650 | Bet365 | 13.3% | 11 |
| Gabriel Arias (TB) | +750 | Bet365 | 11.8% | 26 |
The Top Play: Colson Montgomery
Colson Montgomery carries the shortest home run price in this game at +370 (21.3% implied), and the best number is at Unibet across the 31 books pricing it. On a payout-driven market like home runs, the gap between the best and worst book is real money, so the number you take matters as much as the player you pick.
Best Value: Rhys Hoskins
For more payout, Rhys Hoskins is priced at +412 (19.5% implied), best at DraftKings. Longer home run prices are high-variance by nature, so size these small and treat them as upside swings, not anchors.
Expert picks for this game
These are real plays from OddsShopper experts you can follow on Tails:
- MisterMarkot on Tails (1093-976 graded record) likes Anthony Kay Over 4.5 Total Hits Allowed (+125).
- CharlieChip on Tails (204-186 graded record) likes Chicago White Sox Moneyline (-105).
- JediModi on Tails (553-1213 graded record) likes Sam Antonacci Over 0.5 Total Home Runs (+900).
- JediModi on Tails (553-1213 graded record) likes Colson Montgomery Over 0.5 Total Home Runs (+331).
More from these experts on Cleveland Guardians vs Chicago White Sox. CharlieChip, JediModi, MisterMarkot post full premium cards on Tails. See their cards on Tails.
How to Bet Home Run Props the Smart Way
- Shop every book. The same home run prop can pay 100+ points more at one book than another. OddsShopper scans 100+ sportsbooks so you always take the best number — see the live home run board.
- Mind the price, not just the name. A great hitter at a short price can be worse value than a mid-tier bat the market is sleeping on. Compare the price to the field before you fire.
- Size for variance. Home run props are longshots; keep the stakes small and play the long run.
New to OddsShopper? It scans 100+ sportsbooks in real time and flags the best price on every home run prop (and where it's actually +EV), doing automatically what this article did by hand. Try OS Pro free for 7 days, and code SMARTBET20 takes 20% off your first payment if you subscribe.
FAQ
Who has the best home run odds for Cleveland Guardians vs Chicago White Sox today? Colson Montgomery at +370 (Unibet) is the shortest price; the table above lists the best book for every play. What does “to hit a home run” mean? It's the over 0.5 home runs prop — the player hits at least one home run. The odds and best book vary by sportsbook, so compare before betting. Where can I shop Cleveland Guardians vs Chicago White Sox home run prop odds? OddsShopper's live home run board compares every sportsbook's price in real time so you always take the best number.
Odds shown are the best available as of publication and move quickly. Shop live prices on OddsShopper. Bet 21+ where legal; play responsibly.
